hotuksin

Hotuksin is a traditional Korean herbal medicine composed primarily of the dried roots of *Cynanchum wilfordii* (also known as *Cynanchum auriculatum*), commonly referred to as "hotuk" or "wild foxglove." The name "hotuksin" combines the Korean term *hotuk* (호두, meaning "wild foxglove") with the suffix *-sin* (신), which often denotes a medicinal preparation in traditional East Asian pharmacology.

This herb has been used in Korean traditional medicine (known as *hangwa* or *hanbang*) for centuries, particularly for its purported anti-inflammatory, analgesic, and immune-modulating properties. Modern research has explored its potential benefits, including anti-cancer effects, though further clinical validation is required. Hotuksin is often consumed as a tea or extract, though it should be used cautiously due to potential side effects, such as gastrointestinal discomfort or allergic reactions in sensitive individuals.

The active compounds in hotuksin include iridoid glycosides, such as loganin and secologanin, which are believed to contribute to its pharmacological effects. While traditionally used for conditions like arthritis, sore throat, and respiratory infections, contemporary studies have also investigated its antioxidant and antimicrobial properties. However, its safety and efficacy in modern medical contexts remain subjects of ongoing research.

In Korea, hotuksin is sometimes marketed as a dietary supplement or ingredient in herbal remedies, though regulatory oversight varies. As with any herbal medicine, consultation with a healthcare professional is advised before use, especially for those with pre-existing medical conditions or those taking prescription medications.