Homofermentative LAB, such as Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus, play a pivotal role in dairy industry applications. They rapidly convert lactose and other sugars into lactic acid, thereby lowering the pH of milk and leading to curd formation. The relatively low production of carbon dioxide compared to heterofermentative strains results in a denser curd without the uniform aeration characteristic of bread dough fermentation. In alcohol production, Saccharomyces cerevisiae operates predominantly in a homofermentative manner, converting sucrose or glucose to ethanol and CO₂ while maintaining minimal acetate production, which is crucial for beverage quality.
Industrial and biotechnological fermentation often prefers homofermentative pathways because of their predictable product profiles and higher yields of desired end products. For example, in the manufacture of organic acids such as lactic acid for biodegradable plastics, a homofermentative strain can deliver a consistent product stream with simpler downstream processing. However, the dominance of a single product can also limit the production of ancillary metabolites that might be advantageous for flavor development or functional properties in fermented foods.
In summary, homofermentatiivsed processes are characterized by the conversion of sugars into a single primary metabolite, resulting in streamlined product outputs that are desirable in many industrial, food, and beverage fermentations, while offering contrast to the diversified outputs of heterofermentative pathways.