detD1

DetD1 is a gene symbol used in genome annotations to designate a member of the DetD family of proteins. The exact identity of detD1 varies by organism and database; it is not a single universally defined protein. In many annotations, detD1 is a hypothetical or predicted protein.

In bacteria, detD1 often appears within operons labeled detA–detF or within loci associated with stress response and detoxification. Its assignment is commonly based on sequence similarity to related DetD proteins and on genomic neighborhood, rather than on experimentally verified function.

Predicted function and features: DetD1 proteins are typically 250–350 amino acids long and may lack obvious catalytic motifs. They are frequently annotated as putative oxidoreductases, regulatory factors, or binding proteins. The precise biochemical role remains unresolved in most species, pending experimental validation.

Structure and evolution: Computational analyses suggest varied folds among DetD1 proteins, with some containing domains related to redox chemistry or gene regulation. Conservation is strongest within certain bacterial clades, with divergence observed across taxa, reflecting lineage-specific adaptations.

Status and references: DetD1 entries mainly reflect annotation practices rather than confirmed functions. Researchers should consult primary literature and database records for the organism of interest to obtain the most accurate, up-to-date interpretation of detD1.