coresistance
Coresistance refers to the phenomenon where an organism, particularly a microorganism, exhibits resistance to multiple antibiotics or antimicrobial agents simultaneously. This concept is closely related to multidrug resistance (MDR), though it often implies a more intrinsic or genetically encoded mechanism rather than acquired resistance through mutations or horizontal gene transfer. Coresistance typically arises when resistance genes are located on the same genetic element, such as a plasmid or chromosomal region, allowing the organism to resist several drugs at once.
The emergence of coresistance is a significant concern in clinical settings, as it complicates the treatment
Coresistance is not always fixed; some cases involve overlapping resistance mechanisms, such as efflux pumps that
Understanding coresistance is crucial for public health, as it underscores the need for comprehensive strategies to