cisnerolidol

cis-nerolidol is a naturally occurring sesquiterpene alcohol and one of two geometric isomers of nerolidol, the other being trans-nerolidol. It occurs in the essential oils of a wide range of plants and contributes to their aroma, often described as floral, fruity, or woody.

Chemically, cis-nerolidol has the molecular formula C15H26O. It is an acyclic sesquiterpene alcohol with multiple double bonds in the side chain. The designation “cis” refers to the geometry around one of the double bonds in the chain, and cis-nerolidol can exist in various stereoisomeric forms. In nature, it is typically found together with other terpenes in complex essential oil blends.

Occurrence and sources are diverse; cis-nerolidol has been identified in the essential oils of ginger, jasmine, lemongrass, tea tree, and cannabis, among others. Its relative abundance varies by plant species, tissue, and environmental conditions, making it a common component in many essential oil profiles.

Uses and properties include its application as a fragrance and flavor ingredient due to its characteristic aroma. In addition, cis-nerolidol has been studied for biological activities such as antimicrobial, antifungal, and anti-inflammatory effects in laboratory contexts, although these findings are not yet indicative of clinical efficacy. Like other fragrance compounds, it is primarily regulated for use in cosmetics, foods, and aromatherapy products rather than as a therapeutic agent.

Safety and regulation: cis-nerolidol is generally used at low concentrations in consumer products; it can cause skin irritation or sensitization in sensitive individuals in some cases, so standard safety guidelines and regulatory limits apply.