calcipotriens

Calcipotriene, also known as calcipotriol, is a synthetic analog of vitamin D. It is primarily used topically as a treatment for psoriasis, a chronic autoimmune disease that causes rapid buildup of skin cells, resulting in scales and red, itchy patches. Calcipotriene works by slowing down the growth of skin cells and reducing inflammation, thereby alleviating the symptoms of psoriasis.

This medication is available in various formulations, including ointments, creams, solutions, and foams. When applied to the skin, calcipotriene helps to normalize the keratinocyte differentiation process, which is abnormal in psoriatic lesions. By restoring more typical cell turnover and reducing inflammation, it helps to smooth out the skin and decrease redness and scaling.

Calcipotriene is often used in combination with other topical medications, such as corticosteroids, to enhance its effectiveness and manage more severe cases of psoriasis. While generally well-tolerated, potential side effects can include skin irritation, redness, itching, and dryness at the application site. Systemic absorption can occur, and in rare cases, elevated calcium levels in the blood may be a concern, particularly with extensive use or in individuals with impaired kidney function. It is important to use calcipotriene as directed by a healthcare professional.