allergeenispesifisyys
Allergeenispesifisyys refers to the degree to which an individual’s allergic immune response is directed toward a particular allergen or allergen component rather than to other, related substances. It describes the specificity of the immune reaction, typically mediated by allergen-specific IgE antibodies and, in some cases, T cell responses.
In allergic disease, specific reactivity is most often assessed with IgE-mediated mechanisms. Tests include measuring allergen-specific
Allergen specificity is important because of cross-reactivity. Shared protein epitopes among related allergens can cause sensitization
Limitations include that the presence of sIgE or a positive skin test does not always predict clinical
Examples commonly discussed include peanut Ara h2 specificity associated with true peanut allergy and Bet v