adiponectinlike
Adiponectinlike, or adiponectin-like, is a term used in molecular biology to describe proteins that are structurally and functionally related to adiponectin, a hormone produced by adipose tissue involved in metabolic regulation. In practice, the term is often used to refer to members of the C1q/TNF-related protein (CTRP) family, which share a C1q-like globular domain and a collagen-like stalk with adiponectin. These proteins are secreted, form multimeric assemblies, and are expressed in adipose and other tissues.
Structure and classification: CTRP family comprises several paralogs (CTRP1–CTRP15 in humans). They typically have an N-terminal
Receptors and signaling: adiponectin signals primarily through AdipoR1 and AdipoR2, activating AMPK and PPARα pathways; CTRPs
Biological roles and clinical relevance: adiponectin and adiponectin-like proteins generally promote glucose uptake, fatty acid oxidation,
As a term, "adiponectinlike" is not a single canonical protein but a descriptive label for adiponectin-related