Tyroksiini
Tyroksiini, also known as thyroxine or T4, is a thyroid hormone produced naturally by the thyroid gland and used medically as a replacement therapy for hypothyroidism. In the body, T4 largely acts as a prohormone that is converted in tissues to the more active triiodothyronine (T3), which regulates metabolism, growth, and development.
Medical use and mechanism: Tyroksiini is the standard treatment for overt and many cases of subclinical hypothyroidism.
Pharmacokinetics and dosing: Synthetic thyroxine is typically taken once daily on an empty stomach, as absorption
Safety, monitoring, and interactions: Overtreatment can cause symptoms of hyperthyroidism and increases in heart rate, atrial
Special considerations: Thyroxine requirements may rise during pregnancy and in recovery from some illnesses. Therapy should