Tem1like

Tem1like is a term used in molecular biology to refer to proteins that share structural or functional similarities with the Tem1 protein found in yeast. Tem1 is a key component of the spindle pole body (SPB) in Saccharomyces cerevisiae and plays a crucial role in regulating cell division by acting as a molecular switch that controls the transition from cytoplasmic microtubule organization to nuclear spindle formation.

Proteins categorized as Tem1like often possess a highly conserved GTPase domain, indicating their potential involvement in guanine nucleotide binding and hydrolysis, a common mechanism for regulating protein activity and signaling pathways. These proteins are frequently found in eukaryotes and have been implicated in a variety of cellular processes, including cell cycle control, cell polarity, and cytoskeleton organization.

Research into Tem1like proteins often focuses on their interactions with other cellular partners and their precise roles in mediating specific cellular events. Understanding the functions of these proteins can provide insights into the fundamental mechanisms of cell division and how these processes are conserved or diversified across different species. The discovery and characterization of Tem1like proteins contribute to the broader understanding of cell biology and the intricate regulatory networks that govern life.