SpikeTimingDependent
Spike-timing-dependent plasticity, often abbreviated as STDP, is a form of synaptic plasticity in which changes in synaptic strength depend on the precise relative timing of presynaptic and postsynaptic action potentials. This temporal dependence makes STDP a temporally asymmetric Hebbian learning rule that contributes to the refinement of neural circuits during development and learning. While the exact expression of STDP can vary across brain regions and synapses, the core idea is that the order and timing of spikes shape synaptic changes.
In the canonical pair-based version, if a presynaptic spike arrives shortly before a postsynaptic spike within
Variants of STDP include triplet and more complex timing rules, which can account for additional experimental
STDP has been demonstrated in multiple brain regions, including the hippocampus and neocortex, and remains a