Serologisella

Serologisella is the Swedish adjective used to describe matters related to serology, the branch of immunology that studies serum and its immune components, especially antibodies and antigens in blood. In clinical and laboratory contexts, serologiska or serologiska terms refer to tests, findings, or interpretations that involve serum-based immune responses.

The term stands in everyday use for describing procedures and results in serum analysis. Serology seeks to detect past or present infections, assess immune status after vaccination, or determine exposure to specific pathogens by measuring antibodies or antigens in blood serum. The usage is common in hospitals, diagnostic laboratories, and research settings.

Serological methods rely on antigen–antibody interactions. Common techniques include enzyme-linked immunosorbent assay (ELISA), Western blot, immunofluorescent assays, agglutination tests, and various rapid serological tests. Results are typically reported as the presence or absence of a target antibody or antigen, or as a titer indicating antibody concentration. Serological testing is widely used for infectious disease diagnosis, blood donor screening, transplantation compatibility, and epidemiological studies, as well as for monitoring vaccine-induced immunity.

Limitations of serological testing include cross-reactivity with related antigens, which can cause false positives, and the window period after infection before antibodies appear, which can cause false negatives. Pre-analytical factors such as sample handling and timing can also affect results. Interpreting serological results often requires clinical correlation and, in some cases, confirmation with additional testing.

See also: serology, serological test, antibody, antigen.