SH2

SH2 is a designation used for several distinct concepts across different fields, including aviation, computing, and biology. It can refer to a military helicopter, a microprocessor core, or a protein signaling domain, among other uses.

In aviation, SH-2 Sea Sprite refers to a United States Navy anti-submarine helicopter developed by Hughes Aircraft. It entered service in the late 1950s and saw service with carrier air groups and patrol squadrons during the 1960s and 1970s. Variants and improvements were introduced over time, and the type was gradually retired and replaced by newer helicopters designed for similar roles.

In computing, SH-2 denotes the Hitachi SuperH SH-2, a 32-bit RISC microprocessor core that is part of the SuperH family. Introduced in the mid-1990s, the SH-2 was used in various embedded systems. It is particularly notable for its role in the Sega Saturn game console, which used two SH-2 cores alongside other processors to handle graphics, audio, and system tasks.

In biology, SH2 refers to the Src Homology 2 domain, a conserved protein module found in many signaling proteins. SH2 domains recognize and bind phosphotyrosine-containing motifs, mediating interactions in intracellular signaling pathways that regulate processes such as cell growth, differentiation, and metabolism. These domains are a key component of many signaling cascades and have been widely studied in molecular biology.