RelaxinTests

RelaxinTests is a modular, open-source framework designed to support the analysis and validation of relaxin hormone assay data. The project provides tools for data ingestion from common laboratory formats, calibration curve modeling, quality control, and statistical analysis used in endocrinology research. It aims to enable reproducible analysis and cross-lab comparability of relaxin measurements.

Core components include a calibration module that supports 4-parameter logistic models (4PL) and alternative fits, data normalization, outlier detection, and metrics for assay performance such as limit of detection, precision, and accuracy. The suite also offers statistical tests and methods for comparing assay results across batches, alongside plotting utilities for calibration curves, Bland-Altman plots, and ROC analyses. Reports can be generated automatically in multiple formats, and workflows can be configured via human-readable files to ensure auditability.

Development and licensing: Developed by an international community of researchers and software contributors, RelaxinTests is distributed under an open-source license. The project emphasizes transparent documentation, unit tests, and contribution guidelines to support ongoing improvement. It provides a command-line interface and a library API intended for integration into laboratory pipelines and research projects.

Reception and usage: In laboratory settings, RelaxinTests is used to validate assay performance, establish acceptance criteria for data quality, and facilitate cross-study comparisons of relaxin measurements. While it can streamline analysis, users are advised to apply domain-specific validation and comply with applicable regulatory standards.