Regioselektivitas
Regioselektivitas refers to the preference of a chemical reaction to form a specific isomer or regioisomer over other possible isomers. This phenomenon is crucial in organic chemistry and synthesis, as it dictates the outcome of a reaction and the structure of the resulting product. When a reaction can occur at multiple positions on a molecule, regioselectivity describes the tendency for one position to react preferentially.
Several factors influence regioselectivity. Steric hindrance, where the bulkiness of substituents around a reaction site impedes
A classic example of regioselectivity is the Markovnikov's rule in the addition of hydrogen halides to unsymmetrical
Understanding and controlling regioselectivity is essential for chemists to synthesize desired compounds efficiently and with high