Psoriasiform

Psoriasiform refers to a pattern of skin inflammation that resembles psoriasis, a chronic autoimmune condition characterized by red, scaly plaques. The term is used clinically to describe similar skin lesions that may arise from various causes other than true psoriasis. These lesions often exhibit similar clinical features, such as well-demarcated erythematous (red) patches with overlying silvery scales, though they may lack the typical distribution seen in classic psoriasis, such as the elbows, knees, or scalp.

Psoriasiform eruptions can be triggered by a wide range of factors, including medications (such as lithium, beta-blockers, or antimalarials), infections (e.g., streptococcal infections), or systemic diseases (like lymphoma or sarcoidosis). Occupational exposures, such as exposure to certain metals or chemicals, may also contribute to the development of psoriasiform skin changes. In some cases, the condition may be an adverse reaction to topical or systemic treatments.

Diagnosis typically involves a thorough clinical evaluation, including a review of medical history and potential triggers. Skin biopsy may be performed to rule out other dermatological conditions, such as eczema, fungal infections, or neoplastic processes. Treatment depends on the underlying cause and may include discontinuation of offending medications, topical corticosteroids, or systemic therapies like phototherapy or biologics.

While psoriasiform eruptions share similarities with psoriasis, they are distinct entities and require careful differentiation to guide appropriate management. Proper diagnosis ensures targeted treatment, improving patient outcomes and reducing unnecessary complications.