Postexpositionsprophylaxe

Postexpositionsprophylaxe, also known as post-exposure prophylaxis (PEP), is a medical treatment aimed at preventing the onset of HIV infection after potential exposure to the virus. It involves the administration of antiretroviral medications within a specific timeframe following exposure. The primary goal of PEP is to reduce the risk of HIV transmission by inhibiting viral replication and preventing the establishment of an infection.

PEP is typically recommended for individuals who have been exposed to HIV through certain high-risk behaviors, such as unprotected sexual contact with an HIV-positive partner or needle-sharing with an infected individual. The effectiveness of PEP depends on the timing of administration. It is most effective when started within 72 hours of exposure, but it can still be beneficial if initiated within 96 hours.

The medications used in PEP are the same as those prescribed for HIV treatment, including a combination of at least two antiretroviral drugs. The choice of drugs and the duration of treatment may vary based on individual factors, such as the type of exposure and the patient's health status. Regular medical monitoring is essential to assess the effectiveness of PEP and to manage any potential side effects.

PEP is an important component of HIV prevention strategies, particularly in settings where HIV prevalence is high. It provides an additional layer of protection for individuals who may have been exposed to the virus and underscores the importance of safe sexual practices and needle hygiene to prevent HIV transmission.