Patientendosen

Patientendosen is not a standard term in pharmacology; when used, it describes dose regimens that are tailored to individual patients rather than fixed standard doses. The concept is closely related to personalized medicine and therapeutic drug monitoring, emphasizing that drug exposure and response can vary between patients.

In practice, patient-specific dosing takes into account factors such as age, weight, organ function (especially renal and hepatic), comorbidities, concurrent medications, and, when relevant, genetic differences that affect drug metabolism. Dosing decisions are supported by guidelines, pharmacokinetic calculations, and, in some cases, measurements of drug levels in the blood. In pediatrics, weight- or surface area-based dosing is common; in adults, renal or hepatic impairment often requires adjustments.

Examples of patient-end dosage considerations include antibiotics dosed by weight or renal function, anticoagulants where exact targets matter, and chemotherapy regimens adjusted for body surface area and organ reserve. Therapeutic drug monitoring and pharmacogenetic testing are tools used to refine patient-specific doses and reduce toxicity.

The term itself is not uniformly used in medical literature, and it may appear mainly in informal or educational contexts. The broader practice it describes is well established: providing individualized dosing plans to optimize efficacy and safety. Errors in dosing can occur when patient characteristics are not adequately considered, underscoring the role of clinicians, pharmacists, and decision-support systems.

Related concepts include dosage, dosing regimen, personalized medicine, pediatric dosing, and therapeutic drug monitoring.