NutzenRisikoAbwägungsprozesses
Nutzen-Risiko-Abwägung, or benefit-risk assessment, is a systematic framework for comparing desirable and undesired effects of a medical intervention to inform decision making in health care and policy. It aims to balance potential therapeutic benefits against possible harms in a transparent, evidence-based manner.
Used in drug approvals, vaccines, medical devices, treatment guidelines, payer decisions, and public health programs, it
Methods range from qualitative judgments to quantitative analyses, including explicit weighting and decision-analytic approaches such as
Typical steps involve defining the decision question and context; identifying benefits and risks; collecting and synthesizing
Challenges include incomplete data, bias, and methodological uncertainty; variation in risk tolerance among patients and societies;
The concept is closely tied to risk assessment, pharmacovigilance, and risk-management frameworks, with formal guidelines from