Meclisin

Meclisin is not a widely recognized chemical or pharmaceutical name in standard references. It may be a misspelling or variant of meclizine, an antihistamine commonly used to prevent and treat nausea, vomiting, and vertigo, including motion sickness. If the term refers to a different substance, reliable information may be limited or unavailable.

Meclizine is available over the counter in many countries and by prescription in others. In the United States it is marketed under several brands, such as Antivert, Bonine, and a Dramamine line, as well as in generic forms. It is used to prevent and treat symptoms of motion sickness and vertigo, typically taken by mouth as tablets or chewables. For motion sickness, dosing is commonly 25 to 50 mg taken about an hour before travel, with guidance from a clinician for any additional dosing. Dosing for vertigo can vary and is often adjusted by a healthcare provider based on patient needs and response.

Mechanistically, meclizine is an H1 receptor antagonist with anticholinergic properties. It crosses the blood–brain barrier and reduces vestibular stimulation, which helps mitigate nausea and dizziness associated with motion and balance disorders. Its sedating effects contribute to symptom relief but can cause drowsiness in many people.

Common adverse effects include drowsiness, dry mouth, fatigue, dizziness, and blurred vision. Meclizine should be used with caution with alcohol or other central nervous system depressants and is contraindicated in individuals with certain hypersensitivities or medical conditions. Always follow labeling and consult a healthcare provider for persistent or severe symptoms.