LncRNAt
lncRNAt is a long non-coding RNA (lncRNA), a category of transcripts typically longer than 200 nucleotides that do not encode proteins. Like many lncRNAs, lncRNAt is transcribed by RNA polymerase II and is often capped, spliced, and polyadenylated. Its genomic context can be intergenic or overlap with protein-coding genes in sense or antisense orientation, and multiple transcript isoforms may arise from alternative splicing.
Expression and regulation: lncRNAt expression is frequently tissue- or condition-specific and can change during development or
Functions and mechanisms: lncRNAt may act in cis to regulate neighboring genes or in trans to influence
Research approaches: Investigations rely on transcript profiling and localization studies, along with interaction assays such as
Evolution and relevance: Many lncRNAs show limited sequence conservation across species, though some retain conserved functions