LPLgeen
LPLgeen is a term used in speculative genomics to denote a hypothetical family of genes proposed to encode proteins with lipase-like activity involved in lipid metabolism. The name combines LPL, referring to the lipoprotein lipase family, with the suffix geen as a stylistic variant of "gene." In many thought experiments, LPLgeen members are imagined to carry catalytic domains related to lipases, potentially fused with regulatory elements that determine tissue distribution, substrate preference, and subcellular localization. In these models, expression is often posited in adipose tissue, liver, and muscle, with regulation linked to nutritional state and hormonal signals, though actual expression patterns vary by fictional scenario.
In conceptual evolutionary scenarios, LPLgeen is thought to have arisen by duplication and divergence of ancestral
Critics emphasize that treating speculative concepts like LPLgeen as real can impede interpretation of comparative genomics.