LOSynthese

LOSynthese, sometimes written as LO-Synthese, is a term encountered in several academic contexts to describe a synthesis framework that centers on modular, linear construction of complex products, such as molecules, materials, or software-driven workflows. The exact definition varies by field, but the core idea is to assemble a target from simpler building blocks through a sequence of well-defined steps, enabling traceability and reproducibility.

Chemistry-focused discussions of LOSynthese emphasize architectures that combine small, interchangeable units in a controlled order, often leveraging automated platforms, flow equipment, or iterative cycles. In this usage, LOSynthese promotes standardization of reagents, conditions, and data reporting to facilitate scale-up and rapid optimization.

In computer science or systems engineering contexts, LOSynthese may denote a workflow paradigm that coordinates modular processes or computational steps. Here the emphasis is on orchestration, fault handling, and integration with laboratory-information-management systems or electronic lab notebooks.

Because the term is not widely standardized, LOSynthese appears with varying spellings and scope across sources. It is generally treated as a conceptual framework rather than a single, universally accepted protocol.

Applications cited include chemical libraries, material synthesis, and automated discovery pipelines, where modular design and sequential execution reduce complexity and improve reproducibility. Critics note that the lack of a formal definition can hinder cross-disciplinary adoption.