Isopropylpalmitat

Isopropyl palmitate is the isopropyl ester of palmitic acid (palmitate). It is a colorless to pale yellow, viscous liquid with low water solubility and good compatibility with oils. In cosmetic and personal care products it is commonly used as an emollient, slip agent, and solvent, helping to improve texture, spreadability, and the feel of formulations such as creams, lotions, foundations, and sunscreens. It can also act as a carrier for fragrances and active ingredients.

Production and properties: Isopropyl palmitate is prepared by esterification of palmitic acid with isopropanol, followed by purification. It is typically derived from vegetable oils, such as palm oil, in commercial supply, though alternative synthetic routes exist. The compound is lipophilic, relatively non-volatile, and exhibits low water solubility. It is generally stable under standard formulation conditions, with hydrolysis possible only slowly under extreme pH or high temperatures.

Safety and regulation: In cosmetics, isopropyl palmitate is widely used and is generally regarded as safe. It has low acute toxicity and is not typically a skin sensitizer; however, some individuals with sensitive or acne-prone skin may experience irritation or pore-clogging with certain emollients. Environmental impact is typically modest when used responsibly, and the ingredient is commonly listed in cosmetic ingredient databases and accepted for use in many regulatory regions, subject to regional requirements.

Sustainability considerations: Because it is often derived from palm oil, sustainability and supply-chain considerations apply, including concerns about deforestation and responsible sourcing.