IgEand
IgEand is not a standard term in immunology. If encountered, it most likely represents either a typographical error or a concatenation of IgE with the word 'and' in a phrase such as 'IgE and receptors' or 'IgE and allergic disease.' This article summarizes what IgE is, its roles, and clinical relevance.
IgE is a class of immunoglobulins produced mainly by plasma cells in mucosal tissues and the bone
Upon allergen exposure, IgE bound to these receptors recognizes the allergen and cross-links receptor complexes, triggering
Clinical assessment often includes measurement of total serum IgE and specific IgE antibodies against particular allergens,
Ongoing research explores the regulation of IgE production, the detailed signaling pathways of FcεRI, and novel