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HPV11

HPV-11 is a human papillomavirus type in the genus Alphapapillomavirus. It is considered a low-risk mucosal HPV type because infections rarely lead to cancer. Like other low-risk HPV types, it expresses viral proteins that promote cell proliferation but have limited ability to transform cells into cancerous ones.

The most common clinical manifestations associated with HPV-11 are anogenital warts (condylomata acuminata), typically occurring on

Transmission occurs mainly through sexual contact. Perinatal transmission can contribute to pediatric cases of RRP. Infections

Diagnosis of HPV-11-related warts is usually clinical; laboratories may perform PCR-based typing to confirm the presence

Prevention is supported by vaccination. Vaccines that include HPV-11, such as the quadrivalent Gardasil and the

the
genitals,
perineum,
and
surrounding
areas.
HPV-11
is
frequently
found
together
with
HPV-6
in
these
warts.
In
addition,
HPV-11
is
one
of
the
types
linked
to
juvenile
recurrent
respiratory
papillomatosis
(RRP),
a
condition
in
which
benign
growths
develop
in
the
airway
and
may
require
repeated
surgical
management.
are
common
among
sexually
active
individuals,
but
most
infections
are
transient
and
cleared
by
the
immune
system
within
months
to
a
few
years.
of
HPV-11
in
lesions
or
tissue
samples.
Histological
examination
of
warts
may
show
koilocytosis
in
squamous
epithelium.
nonavalent
Gardasil
9,
reduce
the
incidence
of
genital
warts
and
may
lower
the
risk
of
HPV-11–associated
RRP
in
exposed
populations.
Management
of
existing
warts
involves
topical
therapies
(for
example,
imiquimod
or
podophyllotoxin),
chemical
or
physical
removal,
and
patient
education.