Ganglionlike
Ganglionlike is a descriptive histopathological term used to indicate that certain cells or structures resemble ganglion cells, typically dorsal root or autonomic ganglion neurons, in their appearance. Cells described as ganglionlike are usually large with abundant eosinophilic cytoplasm, a prominent nucleolus, and may be binucleate or show neuronal differentiation within a lesion. The term does not designate a distinct entity but rather a morphological feature observed in various tissues and tumors.
In pathology, ganglionlike elements are most often discussed in relation to tumors that exhibit neuronal differentiation.
Differential diagnosis typically relies on architectural context and immunohistochemistry rather than the term itself. Neuronal markers