Fördosöksstrategier
Fördosöksstrategier refers to the techniques and approaches used in drug development to determine the appropriate dose of a therapeutic agent for optimal efficacy and safety in humans. The primary goal is to identify a dose range that produces the desired therapeutic effect while minimizing the risk of adverse events. These strategies are crucial for transitioning a drug from preclinical studies to clinical trials and ultimately to market approval.
Early phase dose-finding studies, typically Phase I and Phase II clinical trials, are central to this process.
Phase II trials then focus on establishing proof of concept for efficacy and further refining the dose.