FPCN

FPCN, or the Frontoparietal Control Network, is a prominent functional connectivity network within the human brain associated with higher-order cognitive functions. It is widely recognized as a critical component of the brain's executive control system, involved in goal-directed behavior, decision-making, and adaptive learning.

Anatomically, the FPCN encompasses regions primarily situated in the lateral prefrontal cortex, posterior parietal cortex, and parts of the dorsolateral prefrontal cortex. It demonstrates flexible interactions with other major networks, including the default mode network (DMN) and the dorsal and ventral attention networks, allowing it to regulate internal thoughts and external stimuli effectively.

Functionally, the FPCN plays a key role in maintaining attention, working memory, problem-solving, and task switching. Its role in cognitive control enables individuals to suppress distractions, plan actions, and adapt to changing situations. The network's activity is dynamic, shifting in response to task demands and environmental changes.

Research indicates that the FPCN exhibits both intra-network coherence and cross-network communication, facilitating integrative processing necessary for complex cognitive tasks. Functional MRI studies have shown that disruptions in FPCN connectivity are linked to various neuropsychiatric conditions, including attention deficit hyperactivity disorder (ADHD), schizophrenia, and depression.

Understanding the FPCN's structure and function remains a focus of neuroimaging research, contributing to insights into human cognition and potential avenues for therapeutic intervention. Its integrative role in cognitive control underscores its importance in adaptive behavior and mental health.