DruckVolumenDaten

DruckVolumenDaten (PV-Daten) describe the relationship between pressure and volume within a cardiac chamber, most often the left ventricle, during the cardiac cycle. They are typically visualized as a pressure-volume loop that summarizes preload, contractility, afterload, and compliance in a single beat or sequence of beats.

Acquisition is usually invasive. A conductance catheter placed in the ventricle measures instantaneous volume, while pressure is recorded by an intraventricular sensor. Volumes require calibration to convert conductance to absolute units and correction for parallel conductance from surrounding tissue. Admittance methods provide an alternative. Noninvasive estimates exist but do not yield beat-by-beat PV loops with the same fidelity.

From PV loops, several indices are derived. End-diastolic volume (EDV) and end-systolic volume (ESV) define stroke volume; ejection fraction (EF) is SV/EDV. The area inside the loop represents external work performed by the ventricle. The end-systolic pressure-volume relationship (ESPVR) provides a load-independent measure of contractility, while the end-diastolic pressure-volume relationship (EDPVR) characterizes ventricular compliance. Additional parameters include end-systolic pressure (ESP) and end-diastolic pressure (EDP).

DruckVolumenDaten are used in cardiovascular physiology research, pharmacology, and device testing, including assessment of heart failure, valvular disease, and effects of anesthetics or therapies. Limitations include the invasive nature of data acquisition, calibration sensitivity, and artifacts from catheter position and loading conditions. Proper standardization and reporting are essential for comparability across studies.