Desflurane
Desflurane is a volatile inhalational anesthetic used for the maintenance of general anesthesia in adults and older children. It is a halogenated ether delivered through a desflurane-specific vaporizer on anesthesia machines, usually with oxygen or air and sometimes with nitrous oxide. Because it is highly pungent, desflurane is generally not used for inhalational induction and may provoke airway irritation, coughing, or laryngospasm in susceptible patients.
Pharmacokinetics and metabolism are characterized by very low blood-gas solubility, reflected in a rapid onset and
Pharmacodynamically, desflurane produces dose-dependent hypnosis and anesthesia, with vasodilation that can reduce systemic blood pressure. Its
Safety and adverse effects include the potential to trigger malignant hyperthermia in susceptible individuals. Perioperative monitoring