DEETbased

DEET-based refers to products and formulations that contain N,N-Diethyl-m-toluamide, commonly known as DEET, as their primary active ingredient. DEET is a synthetic compound widely used in insect repellents due to its effectiveness against mosquitoes, ticks, and other biting insects. It was first synthesized in 1946 by the American chemist George Goodson at the University of Cincinnati and has since become a standard in public health efforts to prevent mosquito-borne diseases such as malaria, dengue fever, Zika virus, and Lyme disease.

DEET-based repellents work by creating a chemical barrier that disrupts the insect’s ability to detect human scent, thereby deterring bites. The concentration of DEET in a product typically ranges from 5% to 100%, with higher concentrations offering longer-lasting protection. Products with DEET concentrations between 20% and 50% are generally recommended for extended outdoor activities, as they provide several hours of protection with fewer reapplication needs.

While DEET is considered safe when used as directed, concerns have been raised about potential skin irritation, neurological effects, and environmental impact. Studies have generally found DEET to be non-toxic at recommended doses, but some individuals may experience mild skin reactions or sensitivity. The Centers for Disease Control and Prevention (CDC) and other health authorities continue to endorse DEET-based repellents as a safe and effective measure against insect-borne illnesses.

Alternatives to DEET, such as picaridin, oil of lemon eucalyptus (PMD), and IR3535, have also gained popularity, though DEET remains the most widely tested and proven option. Proper application involves applying the repellent to exposed skin or clothing (avoiding the eyes and mouth) and washing it off after returning indoors. DEET-based products remain a cornerstone of insect repellent strategies worldwide, balancing efficacy with practical use in public health and outdoor recreation.