Célfehérjére

Célfehérjére, also known as target protein, refers to a specific protein molecule that a drug or other therapeutic agent is designed to interact with. This interaction is typically designed to elicit a particular biological response, such as activating or inhibiting a cellular pathway. Understanding the target protein is crucial for the development of effective and safe medications.

The identification and characterization of target proteins are key steps in drug discovery. Researchers study the role of specific proteins in disease processes to determine which ones are most likely to be affected by a therapeutic intervention. Once a target protein is identified, scientists then design molecules that can bind to it with high specificity and affinity. This binding can lead to a change in the protein's activity, ultimately influencing the disease.

Many drugs work by targeting specific enzymes, receptors, ion channels, or other proteins involved in cellular signaling or function. For example, many cancer drugs target proteins that are overexpressed or mutated in cancer cells, disrupting their growth and survival. Similarly, drugs for cardiovascular diseases often target receptors or enzymes involved in regulating blood pressure or heart function. The precise mechanism of action of a drug is directly related to the specific target protein it interacts with.