Callosum
The corpus callosum, often referred to simply as the callosum, is the largest white‑matter structure in the human brain. It consists of about 200 million axons that connect the left and right cerebral hemispheres, enabling communication between homologous cortical regions. The corpus callosum arches inferior to the cingulate gyrus and forms the roof of the lateral ventricles, subdividing into four regions: the rostrum, the genu, the body, and the splenium.
Functionally, the corpus callosum integrates motor, sensory, and higher‑order cognitive information across hemispheres, coordinates bilateral movements,
Development and variation occur throughout life. The corpus callosum begins forming early in gestation and continues
Clinical significance and imaging are important for assessment. In epilepsy, surgical disconnection of the corpus callosum
Evolutionarily, the corpus callosum is a characteristic feature of placental mammals and varies in size and