CSFhypothalamus
CSFhypothalamus is a proposed term describing a functional interface by which cerebrospinal fluid (CSF) signals influence hypothalamic neural and endocrine activity. It is not an anatomical structure, but a framework for understanding how molecules in CSF can affect hypothalamic circuits involved in energy balance, reproduction, and stress responses, particularly near the third ventricle and tanycyte-rich regions.
Anatomy and mechanisms: Molecules in CSF can access hypothalamic tissue across ependymal and tanycyte barriers. Tanycytes
Functions and significance: The CSFhypothalamus concept links CSF composition to regulation of appetite, thirst, osmoregulation, circadian
Status and terminology: CSFhypothalamus is not universally standardized and is used primarily as a descriptive term