CNStoxiciteter
CNStoxiciteter is a category used in toxicology to describe adverse effects on the central nervous system (CNS) caused by exposure to chemical, pharmacological, or physical agents. The term, used in several European languages, denotes a spectrum of CNS disturbances rather than a single disease, ranging from mild cognitive slowing and dizziness to seizures, coma, or death.
Common causes include drugs such as opioids, benzodiazepines, antidepressants, and anticholinergics; alcohols and other sedatives; exposure
Mechanisms are diverse and may involve receptor modulation, disrupted neurotransmitter signaling, metabolic derangements, hypoxia, or direct
Clinical features include altered consciousness, confusion, ataxia, dizziness, agitation, pupil abnormalities, seizures, and, in severe cases,
Diagnosis relies on exposure history, clinical examination, and targeted laboratory testing, including toxicology screens and metabolic
Prognosis varies with the causative agent, dose, comorbidity, and timeliness of care. Prevention focuses on exposure