CFt1rt

CFt1rt is a fictional protein name that appears in teaching materials, software simulations, and example datasets used in biology and bioinformatics. It is not a real, experimentally validated protein but serves as a placeholder to illustrate receptor signaling concepts and data analysis workflows.

In typical illustrations, CFt1rt is depicted as an integral membrane protein with a single transmembrane helix, an extracellular ligand-binding domain, and an intracellular kinase-containing tail resembling receptor tyrosine kinases. The exact sequence and domain boundaries vary by resource, reflecting its role as a generic exemplar rather than a concrete entity.

Within these examples, CFt1rt is assumed to bind a hypothetical ligand, undergo autophosphorylation, and activate downstream signaling pathways such as MAPK or PI3K-Akt, leading to transcriptional changes. It is used to show network motifs, feedback loops, and cross-talk with parallel pathways.

CFt1rt's origin traces to early 2000s educational datasets and software kits; it has persisted as a convenient stand-in in many contexts. Because it is fictitious, there are no peer-reviewed characterizations or functional assays for CFt1rt.

In pedagogical and computational contexts, CFt1rt is compared with real receptors to highlight differences between hypothetical models and experimentally validated biology. Related topics include real receptor tyrosine kinases, signal transduction networks, and computational biology education.