CDKrelated
CDK-related refers to proteins and complexes that are involved in the regulation of the cell cycle, DNA replication, and transcription. CDK stands for cyclin-dependent kinase, which is a family of serine/threonine protein kinases that require cyclin proteins for their activity. CDK-related proteins play a crucial role in the control of cell division and are often targeted in cancer research due to their involvement in uncontrolled cell proliferation.
The CDK family includes CDK1, CDK2, CDK3, CDK4, CDK5, CDK6, CDK7, CDK8, CDK9, and CDK10. Each CDK
CDK-related proteins are also involved in the regulation of transcription. CDK8 and CDK9 form complexes with
CDK-related proteins are often deregulated in cancer cells, leading to uncontrolled cell proliferation and tumor formation.
In summary, CDK-related proteins are essential for the regulation of the cell cycle, DNA replication, and transcription.