C7H7Br

C7H7Br refers to benzyl bromide, also known as bromomethylbenzene. It is an organobromine compound consisting of a benzene ring with a CH2Br substituent, giving the molecular formula C7H7Br. It is a reactive, colorless liquid at room temperature that is typically used as an alkylating agent in organic synthesis.

The benzylic carbon in benzyl bromide is activated toward nucleophilic substitution, making it a common reagent for introducing the benzyl group into molecules. It readily undergoes SN2 reactions with various nucleophiles to form benzyl ethers, benzyl esters, and other benzylated products. Because the benzyl group can be removed under relatively mild conditions, benzyl bromide is also employed to install a protecting group for alcohols or amines in multi-step syntheses.

Preparation methods commonly involve converting benzyl alcohol to the bromide, using reagents such as phosphorus tribromide (PBr3) or hydrobromic acid (HBr). Alternative routes include bromination of suitable benzyl precursors. In addition to laboratory-scale use, benzyl bromide serves as an important intermediate in the production of fragrances, pharmaceuticals, and polymer-related reagents.

Safety and handling are important considerations. Benzyl bromide is an irritant and a potentially harmful alkylating agent. It may be moisture-sensitive, hydrolyzing in water to form benzyl alcohol and hydrobromic acid, and it can release hazardous fumes if heated. It should be handled in a fume hood with appropriate personal protective equipment, and stored away from moisture and incompatibles.