Bromointi

Bromointi refers to the process of introducing a bromine atom into an organic molecule, typically through a chemical reaction known as bromination. This reaction is a type of electrophilic aromatic substitution or addition, depending on the substrate involved. Bromine (Br₂) is often used in these reactions, either alone or in combination with catalysts like iron(III) bromide (FeBr₃) or light, which facilitate the reaction by generating bromine radicals.

In aromatic bromination, bromine replaces a hydrogen atom on an aromatic ring, particularly at positions activated by electron-donating groups such as methyl or hydroxyl substituents. This reaction is selective and often occurs at the ortho and para positions relative to the activating group. For example, bromination of toluene yields *o*-bromotoluene and *p*-bromotoluene as major products, with some *m*-bromotoluene as a minor byproduct.

In aliphatic systems, bromination typically involves the addition of bromine across double or triple bonds, such as in alkenes or alkynes. This reaction proceeds via a radical mechanism, especially under UV light or heat, where bromine radicals abstract hydrogen atoms, leading to the formation of brominated products. For instance, bromination of ethene (C₂H₄) produces 1,2-dibromoethane (BrCH₂CH₂Br).

Bromination is widely used in organic synthesis for functionalizing molecules, synthesizing pharmaceuticals, agrochemicals, and specialty chemicals. The reaction conditions and reagents can be adjusted to control selectivity and yield, making bromointi a versatile tool in chemical synthesis. However, bromine is toxic and corrosive, so proper handling and safety precautions are essential when performing bromination reactions.