Bioresorbabilní

Bioresorbabilní, derived from the Latin words "bio" meaning life and "resorbere" meaning to absorb, refers to materials that are designed to be absorbed or degraded by the body over time. These materials are commonly used in medical and biomedical applications, particularly in the fields of tissue engineering, drug delivery, and wound healing. The primary advantage of bioresorbable materials is their ability to integrate with the host tissue, minimizing the risk of foreign body reactions and reducing the need for subsequent surgical removal.

Common examples of bioresorbable materials include polymers such as poly(lactic acid) (PLA), poly(glycolic acid) (PGA), and their copolymers, as well as natural materials like collagen and hyaluronic acid. These materials can be engineered to degrade at specific rates, allowing for controlled release of drugs or nutrients, or to support tissue regeneration. The degradation process typically involves hydrolysis, where water molecules break down the polymer chains, or enzymatic degradation, where specific enzymes in the body break down the material.

The selection of a bioresorbable material depends on various factors, including the intended application, the desired degradation rate, biocompatibility, and mechanical properties. For instance, PLA and PGA are often used in sutures and implants due to their strength and biodegradability, while collagen is used in tissue scaffolds due to its natural compatibility with biological tissues.

In summary, bioresorbable materials play a crucial role in modern medicine by providing temporary support or controlled release mechanisms that are gradually absorbed by the body, thereby promoting healing and regeneration. Their use continues to evolve as researchers develop new materials and optimize existing ones for specific medical applications.