AP1heterodimeeri
AP1 heterodimers are protein complexes formed by the dimerization of two basic leucine zipper (bZIP) transcription factors, Jun and Fos, which belong to the Activator Protein 1 (AP-1) family. AP-1 is a transcription factor complex that plays a critical role in regulating gene expression in response to various stimuli, including growth factors, cytokines, stress, and environmental signals.
The primary AP-1 heterodimers are composed of Jun proteins (c-Jun, JunB, and JunD) paired with Fos proteins
AP-1 heterodimers regulate a wide range of biological processes, including cell proliferation, differentiation, apoptosis, and immune
The formation of AP-1 heterodimers is tightly controlled by post-translational modifications, such as phosphorylation, acetylation, and
In summary, AP-1 heterodimers are essential mediators of cellular responses to extracellular signals, coordinating gene expression