AOMssa
AOMSSA is a software tool used in proteomics to identify peptides from tandem mass spectrometry (MS/MS) data. It operates by comparing experimental spectra against theoretical spectra generated from a protein sequence database, scoring matches to determine the most plausible peptide identifications. AOMSSA emphasizes statistical interpretation of results, providing estimates of confidence for peptide-spectrum matches and allowing researchers to set thresholds for false discovery rates.
AOMSSA emerged in the early era of open-source proteomics software as an alternative to commercial search engines.
The tool accepts standard inputs such as MS/MS spectra and a protein FASTA database, and it supports
AOMSSA has been used in diverse proteomics studies and helped shape discussions around open-source peptide identification