4Hydroxyphenethylamine
4-Hydroxyphenethylamine, also known as 4-hydroxyphenethylamine or tyramine (p-tyramine), is a monoamine alkaloid and a para-substituted derivative of phenethylamine. Its chemical formula is C8H11NO2, reflecting a benzene ring bearing a hydroxyl group at the para position and a two-carbon side chain ending in an amine.
The compound occurs widely in nature as a trace amine. It is produced in the body by
Pharmacology and effects are primarily indirect. Tyramine acts as a substrate for monoamine oxidase and can
Safety and clinical considerations are mainly related to dietary interactions with monoamine oxidase inhibitors (MAOIs). Inhibition
In summary, 4-hydroxyphenethylamine is a para-hydroxylated phenethylamine widely distributed in nature, functioning mainly as a trace