upregellinbased
UpRegellinBased is a term that refers to a class of compounds that are derived from regellin, a natural product isolated from the marine sponge Halichondria okadai. Regellin itself is a potent and selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4), which plays a crucial role in the regulation of glucose metabolism. The development of upregellin-based compounds aims to enhance the therapeutic potential of regellin by improving its pharmacokinetic properties, such as solubility, stability, and bioavailability.
These compounds are designed to maintain the DPP-4 inhibitory activity of regellin while addressing its limitations.
The therapeutic applications of upregellin-based compounds are primarily focused on type 2 diabetes and related metabolic
Research on upregellin-based compounds is ongoing, with efforts focused on optimizing their structure-activity relationships and evaluating