tumorgenome

The tumorgenome refers to the complete set of genetic material, including DNA and RNA, found within a tumor cell. Analyzing the tumorgenome allows scientists to identify specific genetic mutations, alterations, and other molecular changes that drive tumor growth and development. These changes can include point mutations, insertions, deletions, chromosomal rearrangements, and amplification or loss of genetic material. Understanding the tumorgenome is crucial for cancer research and clinical practice. It helps in classifying different types of cancer, predicting how a tumor will behave, and identifying potential targets for therapy. Next-generation sequencing technologies have revolutionized tumorgenome analysis, enabling rapid and comprehensive profiling of tumor DNA and RNA. This data can be used to personalize cancer treatment by matching patients with therapies that are most likely to be effective based on their tumor's specific genetic makeup. Furthermore, comparing the tumorgenome to the normal genome of the patient can help distinguish between cancer-driving mutations and passenger mutations that have no direct role in tumor progression.