trypanotolerance
Trypanotolerance refers to the ability of certain animal species, primarily cattle, to live with trypanosome infections without succumbing to the disease. Trypanosomes are protozoan parasites transmitted by tsetse flies, which cause a range of debilitating diseases collectively known as trypanosomiasis, or sleeping sickness in humans and nagana in animals. While many breeds of cattle are highly susceptible to trypanosomiasis and suffer severe weight loss, anemia, reduced productivity, and death, certain breeds, particularly those indigenous to West Africa, exhibit a remarkable degree of resistance.
This tolerance is not absolute immunity, as trypanosomes are present in the blood of tolerant animals, but
The study of trypanotolerance is crucial for livestock development and food security in sub-Saharan Africa, where