terminaattorinuukleotidi
Terminaattorinuukleotidi, also known as a chain-terminating nucleotide or dideoxynucleotide, is a modified nucleotide that plays a crucial role in molecular biology, particularly in DNA sequencing and some antiviral therapies. Unlike standard deoxynucleotides, which have a hydroxyl group at the 3' carbon position of their sugar ring, terminaattorinuukleotidi lacks this hydroxyl group.
This structural difference is the key to its function. During DNA synthesis, DNA polymerase adds new nucleotides
This property is exploited in the Sanger sequencing method. In this technique, DNA is replicated in the