t2p1dx2

t2p1dx2 is a gene encoding a protein identified in the model organism OrgX. It was first described in genome annotation efforts that aim to catalog protein-coding genes and their potential functions. The symbol t2p1dx2 is used in several public databases to denote this gene and its protein product.

Genomic context: The t2p1dx2 locus is located on chromosome 9 of OrgX and spans about 6.8 kilobases. It consists of three exons and generates at least two transcript isoforms by alternative splicing. The major transcript is roughly 1.1 kilobases in length and is subject to regulation under cellular stress.

Protein characteristics: The encoded protein is predicted to be 410 amino acids long, with a molecular weight near 45 kDa. Sequence analysis identifies a putative nucleotide-binding fold, but no clearly defined catalytic motif has been observed. Subcellular localization is predicted to be cytosolic, with no strong targeting signals.

Expression and regulation: t2p1dx2 transcripts are detected in multiple tissues, with higher expression in brain and liver in OrgX. Expression increases in response to oxidative stress and during certain developmental stages. Promoter analysis suggests regulation by several transcription factors linked to growth and metabolism.

Function and interactions: Experimental data are limited. Knockdown reduces cell proliferation modestly, and overexpression has minimal effect on growth. Proteomic approaches identify associations with RNA processing and ribosome biogenesis factors, pointing to a potential role in RNA metabolism or translation regulation, though direct enzymatic activity remains unconfirmed.