prekvasculisering
Prekvasculisering, or prevascularization, is a strategy in regenerative medicine and tissue engineering aimed at forming functional vascular networks within a tissue construct before it is implanted into the body. The goal is to improve graft survival and rapid perfusion by connecting engineered vessels to the host circulatory system after transplantation.
Methods used to achieve prekvasculisering include in vitro approaches such as seeding scaffolds with endothelial cells,
Applications span various tissues, including bone, muscle, skin, adipose tissue, and other engineered organs or grafts
Limitations and challenges include replicating the full complexity of native vasculature, ensuring stable and mature vessel